Metabolic syndrome increases the risk for cardiovascular disease, stroke, fatty liver disease and diabetes. The multiple components of metabolic syndrome are: abdominal obesity, high triglycerides, low HDL cholesterol, elevated blood pressure, and high fasting blood sugar. The American Heart Association reports that nearly one in six Americans have metabolic syndrome and many may not even realize it.
Individual studies utilizing extra virgin olive oil (EVOO) and omega-3 fatty acids from fish oil separately have demonstrated improvements in lipid profile and reduced overall risk of cardiovascular disease. In this 2015 study, researchers from Brazil wanted to determine if the combination of the two would be even more beneficial.
A total of 81 women and 21 men diagnosed with metabolic syndrome were randomly assigned to one of four groups:

  1. Control group that maintained their usual diet
  2. Fish oil group at a dose of 3 grams per day of omega-3 fatty acids
  3. EVOO at a dose of 2 tsp at lunch and 2 tsp at dinner
  4. Combination of fish oil and EVOO at the dosages listed above

The primary outcomes measures were total and LDL cholesterol, as well as oxidative stress.  Measurements were taken at the start of the study and at 90 days. The researchers found that the combination of fish oil and EVOO produced statistically significant decreases in metabolic syndrome markers when compared to the other groups. The combination also appeared to have a synergistic ability to neutralize free radicals and reduce oxidative stress, which are key factors in the development and progression of metabolic syndrome.
Diet and supplement synergy is an important consideration when creating comprehensive treatment plans. In the case of metabolic syndrome, the combination of EVOO and fish oil makes sense. While this study was fairly small, it provides compelling preliminary evidence that the synergistic combination of EVOO and omega-3 fish oils can reduce oxidative stress and lower both LDL and total cholesterol.
Venturini D, Colado Simao AN, Ragassi Urbano M, Dichi I. Effects of extra virgin olive oil and fish oil on lipid profile and oxidative stress in patients with metabolic syndrome. Nutrition. 2015;31:834-840.


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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.