Four Factors in Successful Weight Management – And how to manage them with supplementation

As we move into spring and motivation toward weight loss grows, let’s take a look at four of the most important aspects of a successful weight loss regimen, and which nutrients can support those processes.
Perhaps the most well-known of all weight loss factors, thermogenesis is what we think of when we talk about the good kind of sweating. The term “burning fat” comes to mind. It has been shown that some thermogenic supplements (in combination with exercise) have the ability to increase metabolic rate.1
The mere production of heat is a defining aspect of weight loss, and finds support from a number of ingredients, including green tea, which offers a high yield of epigallocatechin-3-gallate (EGCG). EGCG alone has been shown to support fat oxidation and increased thermogenesis in obese men, indicating that this one catechin has the power to promote weight loss.2
Hormonal Factors
Adiponectin, leptin, cortisol and DHEA can play huge roles in weight loss or gain. Stress hormones like cortisol and DHEA can lead to excessive food cravings and added fat storage. Adiponectin modulates glucose regulation and fatty acid catabolism; maintaining the amount the body secretes from adipose tissue is highly valuable to weight management efforts. Raspberry ketone has been shown to increase lipolysis and oxidation of fatty acids in some adipocytes.3
To maintain normal cortisol and DHEA levels, a combination of magnolia and phellodendron extracts works by binding to stress receptors in the nervous system, without addressing those receptors that could produce sedative effects. Bacosides are further helpful in the process of stress management, aiding in neural repair through enhancing kinase activity and restoration of synaptic activity.4
Insulin Resistance
Insulin affects the way the body converts calories into fat, and insulin resistance has effects on the liver enzymes that produce cholesterol, making improved insulin sensitivity a key factor in supporting weight loss.
Some natural ingredients, like cinnamon, are known to directly address insulin sensitivity. Naturally occurring polyphenols in cinnamon have been shown in study subjects to improve fasting blood glucose, systolic blood pressure, percentage body fat and increased lean body mass.5 The polyphenols of a new tea crossbreed from Kenya may also produce beneficial action. Laboratory research suggests purple tea with GHG extract may work through inhibiting lipase activity in the pancreas, helping to reduce fat absorption.
Another, more popular and well-known tea has also exhibited beneficial effects on insulin resistance, and therefore is a welcome addition to a successful weight loss regimen. One such study produced the following results:
“After 12 weeks of green tea supplementation, the green tea group had lower fasting plasma levels of glucose, insulin, triglyceride, and free fatty acid than the control rats. Insulin-stimulated glucose uptake of, and insulin binding to, adipocytes were significantly increased in the green tea group. In experiment 2 (in vitro study), a tea polyphenol extract was used to determine its effect on insulin activity in vitro. Green tea polyphenols (0.075%) significantly increased basal and insulin-stimulated glucose uptake of adipocytes.”6
Because adiponectin is intricately involved in glucose modulation, its maintenance is, of course, highly important to insulin resistance.
The Detox Element
Cleanse diets are always trending, and though many of these fads are actually unhealthy approaches, there is something to the idea that detoxing promotes weight loss. A healthy supplement regimen with nutrients that influence each phase of the detoxification process can remove metabolic wastes and chemical accumulations that may affect obesity. Weight loss occurs through increased thermogenesis as the body rids itself of toxins.
Milk thistle’s active constituent silymarin and nutrients like l-cysteine stimulate liver enzymes to break toxins down, while curcumin promotes bile production to help the elimination process.
Antioxidants are a crucial component of the detoxification process. Nutrients that bind to toxic substances or help to convert them into other, less harmful substances, are also crucial; Glutamine converts excess ammonia into other amino acids, amino sugars and urea to support the detoxification process.7
Article provided by DaVinci Labs*

 1. Bergstrom, H, et al. Jour Strength & Conditioning Research 2014;28(8):2154-63
2. Boschmann M, Thielecke F. Jour Amer College of Nutr 2007;26(4):389S-95S
3. Park KS. Planta Med 2010;76:1654–58
4. Singh HK, Dhawan BN. Indian Jour Pharma 1997;29(5):359-65
5. Anderson RA. Proc Nutr Soc. 2008 Feb;67(1):48-53.
6. Wu LY, Juan CC, Ho LT, Hsu YP, Sun Hwang L. J. Agric. Food Chem 2004;52(3):643–48
7. Shen J, Sibson NR, Cline G, Behar KL, Rothman DL, Shulman RG, Dev Neurosci. 1998;20(4-5):434-43.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.**This blog was written by an outside source. This blog does not necessarily reflect the views or positions of Natural Partners.